How can i remove spyware or adware, that most cannot remove?

Everytime I do a search no matter what it is the same stuff comes up first such as ''top 10 credit cards'' and etc,,, I know I have something as my ad-aware keeps removing some of my index.dat files. I have tried ccleaner, norton 360, Mcafee, ad-aware and although each finds something, I can't seem to get rid of this thing. Any other ideas...None of these come up with anything other than my index.dat files.

How can i remove spyware or adware, that most cannot remove?antispam

Try Adaware2007

http://www.download.com/Ad-Aware-2007-Fr...

Make sure its fully updated first before you scan.

How can i remove spyware or adware, that most cannot remove?avast

There is only one answer to this. You need to get a more powerful and Effective anti-spyware tool.

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You have malware installed on your system. If you follow all the following steps it should get rid of your problem and prevent future problems. All programs listed are free.